5-HTP SUPREME is a powerful antioxidant blend especially created for positive mood, relaxation and appetite control. 5-HTP is the precursor to the neurotransmitter serotonin, converts directly into serotonin in the brain. Serotonin has many profoundly important functions, including a role in sleep, appetite, memory, learning, temperature regulation, mood, sexual behavior, cardiovascular function, muscle contraction, and endocrine regulation. L-Lysine helps decrease the body’s cortisol levels, a hormone that may promote added feelings of anxiousness, especially if put into stressful environments. Vitamins B6 and Folate help increase mental sharpness and mood. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
NATTURA 5-HTP SUPREME – 90 Capsules
✅ Powerful Antioxidant Blend Especially Created For Positive Mood, Relaxation and Appetite Control (with 5-HTP, L-Tyrosine, L-Lysine, Vitamin B6, Folate (Folic Acid), Vitamin C (Ascorbic Acid), Calcium).*
✅ 5-HTP: Precursor to the neurotransmitter serotonin, converts directly into serotonin in the brain. Serotonin has many profoundly important functions, including a role in sleep, appetite, memory, learning, temperature regulation, mood, sexual behavior, cardiovascular function, muscle contraction, and endocrine regulation.*
✅ 5-HTP and L-Tyrosine have a synergistic effect on each other, helping to significantly boost your mood.*
✅ L-Lysine helps decrease the body’s cortisol levels, a hormone that may promote added feelings of anxiousness, especially if put into stressful environments.*
✅ Vitamins B6 and Folate help increase mental sharpness and mood.*
As a dietary supplement take one to four capsules daily once or twice daily, preferably in divided doses, with a meal or a glass of water. Store tightly closed in a cool, dry place.
Do not exceed recomanded dose. If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement. Discontinue use and consult your healthcare practitioner if any adverse reaction occur. Keep out of reach children. Do not use it outer bottle seal is missing or damaged.
*These statements have not been evaluated by the Food and Drug Administration. This products is not intended to diagnose, treat, cure, or mitigate any disease.
DL (verified owner) –
Great combination of ingredients that seem to work synergistically with 5-HTP!
Kay (verified owner) –
Same as Neuroreplete
My doctor prescribed “Neuroreplete” which is essentially the same combination of supplements in this brand and the same price; but the former can only be purchased through a physician. The combination is well researched and based off “The Mood Cure.” The doses are high and you should not play around with them, but I will tell you that I was suffering from severe depression and took 4 at 7 AM and 4 at 4 PM. Empty stomach. The L-Lysine gave me back my long lost motivation, energy (though not all), and desire. SSRI’s never worked for me so it’s unclear if the 5-htp helps at all. I still feel depressed – why 4 and not 5 stars – but it may cure others depression.back my long lost motivation, energy (though not all), and desire. SSRI’s never worked for me so it’s unclear if the 5-htp helps at all. I still feel depressed – why 4 and not 5 stars – but it may cure others depression. The BEST part is that there are NO side effects because you are giving your body what it lacks not fooling it into not recycling neurotransmitters like antidepressants do.
Dianne (verified owner) –
Great product and made such a difference!
Ina (verified owner) –
I have been taking this supplement for about two months …
I have been taking this supplement for about two months. It definitely improved my mood and I seem to have less food cravings.
cocolmm (verified owner) –
Good appetite suppressant
I thought it helped decrease my appetite a lot.
Mikilyn (verified owner) –
I just got this… I am very …
I just got this…I am very excited to try this product…I think it has a lot of benefits in one product!!
Sorin (verified owner) –
One of the best I found…
One of the best supplements I found for mood lifting and relaxation. Great combination of ingredients. I bought it from their website, but it is offered at a discounted price on Amazon.
windhorse (verified owner) –
Meh, Undecided if I like it.
Sometimes it seems to work and other days it doesn’t. I got it both because of the high percent of 5 star reviews and I thought the combination of L-Tyrosine and 5htp would help me with mild depression, mood swings, lack of focus. It may be helping with curbing appetite though. it could be that I need to take a consistant amount every day for a longer period for it to build up in my system; I don’t know.
Kathy Perretta (verified owner) –
helps you sleep better and reduces cortisol levels
Everyone should take this supplement. It works well for biological response to stress, helps you sleep better and reduces cortisol levels. I take it every day and it helps with my anxiety. I received a discount for the exchange for my review.
lyannam (verified owner) –
This supplement is awesome!
I have been taking this supplement for about a month now mostly for my anxiety and moodiness. The results have been amazing. My anxiety has reduced significantly & my mind is clear and focused. I also noticed that my appetite and food cravings have reduced and I feel full faster. This supplement is awesome and I will continue to take it!!!
Jennifer Pruett (verified owner) –
I am usually nervous to try new supplements, my stomach doesn’t usually respond well to concentrated vitamins. But after reading the reviews, I’m honestly excited to try this one. It sounds like it just might address (and actually remedy!) many of my problems. I will update once I’ve tried it, I have high standards for these sorts of things.
Amanda (verified owner) –
After a week of taking my sleep and mood has …
After a week of taking my sleep and mood has improved, doesn’t take as long to fall alseep and less irritable. The only con I have is I wake up with headaches.
Fashionista (verified owner) –
not really feeling a big difference with this one.
Anthony T. (verified owner) –
Absolutely great!!! I use it daily.
Jesus Lemus (verified owner) –
it works but it takes like a week or 2 to feel it the dosis …
it works but it takes like a week or 2 to feel it the dosis that i think its better its 3 or 4 caps during the day at the end i was using just 2 one when i woke up and another one to sleep i noticed that after i woke up it was really hard for me to get out of bed so keep that in mind if you take to much it would make you dizzy, great pills overall i take mdma like once every 15 days in partys or ravers that depletes your serotonin so its really helps with the comedown the days after i have notice a difference taking these much more emphatic!!
ashley (verified owner) –
I love these, really helping me aid in withdrawing of SSRI, just bought a second bottle
Bobbi Billard (verified owner) –
I swear by this 5HTP by Naturra!
I’m very happy with this brand. I’ve purchased several times now and will stay loyal to this company. I had read that it is best to take 5HTP in conjunction with L-Tyrosine (prevents an imbalance that causes dopamine levels to drop), Vitamin C and B6 (which are very important for absorption). Nattura’s product allows me to take all of these in one single pill. So convenient and it saves you money from having to buy a bunch more vitamins!Taking 5HTP has helped me so much with appetite control. I’m on the Paleo diet and it’s really strict. Since I started taking this, I don’t struggle with cravings or desire to eat more than I should. I’m sold! As far as I’m concerned this is a magic pill. I’ll be taking this as long as they keep selling it.
Meli (verified owner) –
I recommend the product as a supplement (for those days when …
This is an hinest opinion for discounted price. Have been using the product a couple days now. I recommend the product as a supplement (for those days when you dont feel like working or going to work) but by all means not an antidepressant or such. Just a lift to push you.
Diane (verified owner) –
… product for about 10 days and have already had good results. It cuts down my stress eating by …
I have only been using this product for about 10 days and have already had good results. It cuts down my stress eating by half. It also helps with my mood and anxiety. The jury is still out for helping with sleep. I would recommend this product.
J. Brown (verified owner) –
Replaces 3 of my supplements
I was already taking a different 5-HTP supplement that I was really happy with when I received this one, but this one is much better. Not only does it have more vitamin B6, but it also has 500 mg of vitamin C and 200 mcg of folic acid, which is extremely important to me. I always try to increase my vitamin C intake during the school year because of all the germs coming home with my little one. Now, I can just take this supplement and get all the vitamin C I need for the day. I was also taking melatonin at night to help me sleep, but this seems to be doing the trick. Thank you for such a great product! It’s nice to just take the one supplement instead of three 🙂
Dee (verified owner) –
give it a try.
I noticed my mood was a little better at times. I sont think i noticed any extra energy though. But i will keep using it and see. I would recommend it if u need a mood lift.
Amzn Customer from Conn (verified owner) –
VERY happy so far
VERY happy so far! I obtained this via a promotion, but I have been putting it in my morning smothie for the past few days and have been noticing a difference. I hope this keeps upI will try to update in a few weeks
Daneygurl (verified owner) –
So Far, So Good
So far, it seems to work. I have anxiety & I’ve taken it several times when I felt my heart rate going up. Typically, when anxiety starts, it lasts at least a few ours. The anxiety doesn’t seem to last as long when I take these – I feel myself calming faster than I normally would. I haven’t been taking them very long, so I will try to come back and post an update after several months or so.6/2/16 – Still taking these as needed for anxiety and having he same results as above. The price is great and these are going to last me a while!
jean dixon (verified owner) –
Excellent product I used to purchase under a different name from my healthcare practitioner. So grateful to have found the same dosages in your product!!
Les S. Moore (verified owner) –
Cost Effective and just plain Effective
I got a discount for this review. I have been taking 5-HTP for years (along with GABA and mucuna pruriens) and am used to paying about $30/bottle which is really not much per month when compared to pharmaceuticals which are, in my opinion, too strong and not as effective. This brand of 5-HTP was constent with other brands I have found to be effective as a mood stabilizer/lifter and generally helps maintain a sense of well being (without making me feel “weird” like prescription psychoactives).
Sandbagger (verified owner) –
Not sure if it works, but it came quickly …
Not sure if it works, but it came quickly and in tact. Received this for free in exchange for my honest review.
Ryan (verified owner) –
Fantastic supplement that ensures you are getting a well-balanced blend of micronutrients!
I have been taking this supplement for about a month now to self-medicate my anxiety. As an aspiring clinician, I understand how damaging psychoactive medications can be and that it is much better to fix the underlying issues (i.e. positive thinking, being active, etc…). This blend of micro nutrients is perfect to facilitate a healthy mind and you will feel more alert and overall stable/level-headed if you follow the dosing. I used to need coffee in the morning take the edge off my anxiety, now I don’t need caffeine at all. Overall I feel more relaxed and ready to take on the day. I know a lot of people think that these supplements are not necessary but fact of the matter is you probably are not getting 100% of the nutrients your body needs so better safe than sorry. I thought I had a superb diet and was getting a good blend of nutrients, but taking this supplement has taught me that I am not the nutritionist I once thought.Pros:1.) Work as advertised.2.) No icky taste.3.) No upset stomach after taking as directed.Cons:NONE!
O (verified owner) –
Helped me get to sleep after a heavy metal detox messed with my balance. Helped shut off a brain that was having trouble shutting down on its own.
Kelli H. (verified owner) –
Works good only if you keep up with it everyday.
Liza (verified owner) –
This is a really good supplement to lift your mood. I got it to review it honestly and so far I love it.
Erica O. (verified owner) –
Two thumbs up
francesca (verified owner) –
This is great to take before bed
This is great to take before bed, so you get a restful sleep. I did get this as a promo, but for me, it helps me sleep through the night. There is a difference in sleep pattern when I don’t take it, which is interrupted sleep all night..
LilBlueEyes (verified owner) –
Bottle looks good and everything came as it was supposed to. I’m hoping that after long term use it will improve my mood, I do get a little more perky during the day when i take the supplements. So that’s a good sign, I will come back after I finish the bottle and add onto my review.
Sandra Davis (verified owner) –
… frustration and mood swings plus I am also sleeping better.
It has truly helped with controlling frustration and mood swings plus I am also sleeping better.
C.Sims (verified owner) –
A great alternative to Medically Prescribed Chemical Drugs
I purchased these as an alternative to chemicals while I was suffering acute depression from the passing of my service dog. I know that they do work (at least for me) as far as calming me down and relaxing me so I sleep through the night. I take them cautiously during the day to control my appetite and at the same time provide my body with the nutrition I know it is lacking from the lack of attentiveness to my eating pattern. When one is under a great deal of stress they often eat just to “pass time” away. My sleep pattern was all messed up. I was sleeping maybe 2 hours and back awake crying. Hitting the refrigerator to find something to eat just to occupy me when I would awaken. I have been taking the supplement for a month now and I can tell the difference when I don’t take them prior to bed and when I do.
WayneStain (verified owner) –
Works very well. Would recommend and probably purchase again! They made my mood better and also helped with the snacky cravings I get in between meals or when I am bored.
Justin (verified owner) –
The bottle looks cool. I have not tried it yet thouGh.
SarahJD (verified owner) –
but didn’t like the way it made me feel
I have anxiety. I used to take a prescription medication for it, but didn’t like the way it made me feel. 5-HTP calms me down without making me feel out of it like prescription anxiety medications do.
Ron (verified owner) –
has been sleeping better and her mood swings have all but disappeared
I got this product for my wife after doing some research on the product. It really has made a significant difference in her mood. She tells me she has less anxiety, has been sleeping better and her mood swings have all but disappeared. I have seen a big difference in her attitude and that is good for her and me. If this continues to be the case then this stuff is worth it’s weight in gold. I will continue to buy this product as long as her attitude and mood stays as it has been the last week.
Amazon Customer (verified owner) –
This is definitely controlling appetite.
Anna Bates (verified owner) –
I have started using it as soon as its arrived. I have not felt so much different. I have slept well though for two days. My stress seems a bit better too. I will keep using it and update the differences. No problem at all with it so far.
mary mccullough (verified owner) –
I recieved this product, took it as instructions indicated……After 2 days of using, I must say that it did work! My cravings were cut, appetite was not as prevalent(didn’t eat as much), and memory seemed somewhat better. I did not weigh myself befor taking, so i can not honestly state that its good for weightloss.Overall….. I would recommend it for the usage i had results for.
P.D. (verified owner) –
Not a miracle thing, but I feel like they help.
NOTE: Talk to the appropriate medical professional about your own situation before taking medical suggestions from a product review.It’s somewhat anecdotal, but I do feel like they help. Hard to say more beyond that. So, to make sure I have enough content, I’ll quote Louis, who says, “All I know is I’m grabbin’ PILLS!”
S. Martin (verified owner) –
Appetite Control w/o shakiness.
This is best appetite control I’ve found. I take 2 around 4pm, and it keeps me from chewing my arm off. Costs way less then those magazine products that all seem to be a dollar-a-day or more.
Debie L. Bodjanac (verified owner) –
Good for depression!
This natural supplement helps ease depression and I would also say it helps with sleep too. I would recommend for anyone that has mild/medium depression. This is the 3rd jar we ordered and plan to continue with the dose of 4 per day
Shelly (verified owner) –
Product gives you results, no joke
This is a really good product. My appetite is really low, I’m sleeping good at night AND I have lost 7 pounds in 3weeks. I havent lost weight in over in a year , so I am tickled pink. This has all been caloric based as I can not exercise like most folks can. The only thing that I notice is at night I get a bit of a dry mouth. But a drink of water and I’m good to go. You know, nothing is ever a “miracle” pill, but this has really provided good results for me. Oh and by the way, no one prompted me or gave me anything to post this. I’m just another person struggling to lose weight that can’t exercise looking for something that will help. Give it a try..what do you have to lose?
Moon72 (verified owner) –
Not as effective at the NOW brand ones
Hidden Dragon (verified owner) –
Positive experience in treatment-resistant depression and fibromyalgia
I don’t normally write long reviews (unless I’m complaining), but I hope this might help others looking for options for depression and fibromyalgia that might complement or even reduce standard drug treatments following discussion with their doctor.Appears to be a good quality, well-packaged product – bottles have anti-tamper seals. Capsules are largish but not excessively (have seen larger) and easy to swallow with sufficient water (max daily dose is 4 capsules but this should preferably be split into 2 caps twice a day, so not too onerous).Although much longer expected delivery dates appear on the order, I have received several orders within 5-6 days (delivered from the US) and the seller has dispatched quickly. Delivery costs from US partly explain high cost of this product in the UK. Have given good review to the seller for attentive service/amazon mail contact and delivery.Why am I taking this? Firstly, I am not a supplement/health fanatic, in fact a big sceptic, and always look at the science and research behind anything I take, though please note that I am not making any medical or product recommendations or claims here and you should always consult a suitably qualified/specialised doctor if you have a health issue or taking other medications, even with certain supplements that appear to be ‘natural’.That said, I have had severe, treatment-resistant depression for >4 years. I usually cannot tolerate even the lowest effective doses of antidepressant drugs due to side effects e.g. lethargy/sedation, increased agitation, irritability, dissociation. As many prescription antidepressants aim to alter brain 5-HT/serotonin, dopamine and noradrenaline biochemistry, I started looking into how to use diet (difficult to achieve doses) and later supplements to influence this system and found early research evidence of some efficacy in depression, especially for 5-HTP. I then found theory papers on using a ‘balanced’ approach to amino acid supplements and co-factor vitamins in depression, though the clinical research evidence is not of great quality (e.g. no large-scale, randomised, controlled trials). The theory is that if you take 5-HTP alone to boost brain serotonin, this leads to depletion in dopamine; as tyrosine will in theory increase dopamine levels, taking this as well negates the imbalance. Sounds rational in theory though I’m not sure there is definitive proof of this balance being achieved in the brain with supplements. The various vitamins/calcium in this product are included to act as co-factors in the various pathways involved in the conversion of 5-HTP and L-tyrosine in the brain and elsewhere to the desired active neurotransmitters.So despite my great scepticism, as all prescription drugs and psychological interventions had previously failed, I proceeded cautiously. Initially I tried taking the individual ingredients bought separately but this required around 10 tabs/caps twice a day – miserable experience but I got some long-awaited benefit within a couple of weeks (antidepressants also have a lag period in effectiveness).Then I happened to find 5HTP-Supreme, which contains all the ingredients in a capsule (it’s similar to another US product being promoted by US docs privately with different dose recommendations and price tags). I started on 5HTP-Supreme and noticed improvement in my mood continued but it’s more convenient with only 4 capsules a day. Negative thinking, suicidal thoughts and concentration also have improved. I need to try a supplement holiday in a few months to be certain that the supplement is having the desired effect vs. a normal fluctuation in the illness. A large proportion of antidepressant efficacy is placebo but, even if this applies to 5HTP-Supreme, I’m accepting this for the benefit it appears to have brought with, for me at least, minimal side effects. Long-term there is anecdotal evidence of tolerance (effects wearing off) to amino acid supplements for some individuals, but I’ll cross that bridge if I come to it using breaks from taking the supplement and/or higher doses.Side effects I experienced – mild heart burn but not when taken with/after food; and possible worsening of insomnia (but need a supplement holiday to confirm this is likely due to the supplement and not the depression).Bear in mind that this is just one person’s experience and I have not found data on very long-term safety of the individual amino acids, though no warning indicators either (more data exist on long-term use of the vitamins/calcium in the product, which are in high dose so take care when combining with other supplements). You also need to check with your doctor and reliable online sources for any potential interactions with other medications you might be taking and before reducing any medications.Even more anecdotally, my mother has started on this 5HTP-Supreme as she has chronic fibromyalgia (severely painful muscles, insomnia and fatigue) with consequent depression. There is even less quality evidence to support the use of 5HTP in fibromyalgia although some patients find it effective looking at blogs. As nothing has worked for my mum in decades and she gets depressed with the condition, she gave 5HTP-Supreme a try recently, starting with an initial test dose of 1 capsule, then 2 etc increasing over 7 days (she’s elderly and small). Her initial 4 weeks suggests subjective improvement and, after another 4 weeks at this level of improvement, she plans to reduce very slowly (one at a time) her really heavy pain killers, one of which she has become dependent upon.
bardel (verified owner) –
im feeling much better and sleep very well now
these tablets helped me a lot, im feeling much better and sleep very well now,i just take one in the morning and one at night. worth every penny.
imJack (verified owner) –
will never be off these again. Was prescribed by my doc – and what he provided was 4 times the price. So I went on a hunt to find the exact same ingredients as his brand, and these were the only ones I could find. Really great value.